They also called on President Muhammadu Buhari to reject James Faleke if nominated as a replacement for the late Minister of State for Labour, James Ocholi, who died in an auto crash in March 2016.
Faleke is believed to be Tinubu's stooge whom he is planning to get appointed as Ocholi's replacement.
This was made known in a statement issued in Lokoja on Monday and jointly signed by the party's leaders from Kogi West, Suleiman Ejibunu and Richard Asaje.
They warned that if Faleke gets the ministerial slot of Kogi state, it would cause "serious crisis" in the party.
"If at all Faleke and his godfather, Bola Tinubu, deserve any and not the ministerial slot of Kogi State to avoid serious crisis in the Kogi APC as such a move may lead to the exit of every prominent, loyal and committed member of the party while aggaravating the fractionalisation of the party along many divides.
"We are also unequivocally resolute to stop Tinubu's expansion into Kogi state or any state in the North-Central, we are determined to push out all his cohorts from Kogi come 2018/2019. It is a task that must be done through all legal/political means. They have failed and they will continue to fail."